PRP Literature Reviews
SHOULDERS/ROTATOR CUFF:
Chen X, Jones IA, Togashi R, Park C, Vangsness CT Jr. Use of platelet-rich plasma for the improvement of pain and function in rotator cuff tears: A systematic review and meta-analysis with bias assessment. Am J Sports Med 2020;48:2028-2041.
https://pubmed.ncbi.nlm.nih.gov/31743037/
Peng Y, Li F, Ding Y, et al. Comparison of the effects of platelet-rich plasma and corticosteroid injection in rotator cuff disease treatment: A systematic review and metaanalysis. J Shoulder Elbow Surg 2023;32:1303-1313.
https://pubmed.ncbi.nlm.nih.gov/36868297/
Hurley ET, Lim Fat D, Moran CJ, Mullett H. The efficacy of platelet-rich plasma and platelet-rich fibrin in arthroscopic rotator cuff repair: A meta-analysis of randomized controlled trials. Am J Sports Med 2019;47:753-761.
https://journals.sagepub.com/doi/10.1177/0363546517751397
Hurley ET, Colasanti CA, Anil U, et al. The effect of plateletrich plasma leukocyte concentration on arthroscopic rotator cuff repair: A network meta-analysis of randomized controlled trials. Am J Sports Med 2021;49:2528-2535.
https://pubmed.ncbi.nlm.nih.gov/33332160/
KNEES:
Smith PA. Intra-articular Autologous Conditioned Plasma Injections Provide Safe and Efficacious Treatment for Knee Osteoarthritis: An FDA-Sanctioned, Randomized, Double-blind, Placebo-controlled Clinical Trial. Am J Sports Med. 2016 Apr;44(4):884-91. doi: 10.1177/0363546515624678. Epub 2016 Feb 1. PMID: 26831629.
https://pubmed.ncbi.nlm.nih.gov/26831629/
Crowley JL, Soti V. Platelet-Rich Plasma Therapy: An Effective Approach for Managing Knee Osteoarthritis. Cureus. 2023 Dec 19;15(12):e50774. doi: 10.7759/cureus.50774. PMID: 38116024; PMCID: PMC10729545.
https://pubmed.ncbi.nlm.nih.gov/38116024/
Cole BJ, Karas V, Hussey K, Pilz K, Fortier LA. Hyaluronic Acid Versus Platelet-Rich Plasma: A Prospective, Double-Blind Randomized Controlled Trial Comparing Clinical Outcomes and Effects on Intra-articular Biology for the Treatment of Knee Osteoarthritis. Am J Sports Med. 2017 Feb;45(2):339-346. doi: 10.1177/0363546516665809. Epub 2016 Oct 21. Erratum in: Am J Sports Med. 2017 Apr;45(5):NP10. doi: 10.1177/0363546517700110. PMID: 28146403.
https://pubmed.ncbi.nlm.nih.gov/28146403/
Rodríguez-Merchán EC. Intra-Articular Platelet-Rich Plasma Injections in Knee Osteoarthritis: A Review of Their Current Molecular Mechanisms of Action and Their Degree of Efficacy. Int J Mol Sci. 2022 Jan 24;23(3):1301. doi: 10.3390/ijms23031301. PMID: 35163225; PMCID: PMC8836227.
https://pubmed.ncbi.nlm.nih.gov/35163225/
Patel S, Dhillon MS, Aggarwal S, Marwaha N, Jain A. Treatment with platelet-rich plasma is more effective than placebo for knee osteoarthritis: a prospective, double-blind, randomized trial. Am J Sports Med. 2013 Feb;41(2):356-64. doi: 10.1177/0363546512471299. Epub 2013 Jan 8. PMID: 23299850.
https://pubmed.ncbi.nlm.nih.gov/23299850/
HIPS:
Lim A, Zhu JB, Khanduja V. The Use of Intra-articular Platelet-Rich Plasma as a Therapeutic Intervention for Hip Osteoarthritis: A Systematic Review and Meta-analysis. Am J Sports Med. 2023 Jul;51(9):2487-2497. doi: 10.1177/03635465221095563. Epub 2022 Jun 7. PMID: 35971803; PMCID: PMC10353029.
https://pubmed.ncbi.nlm.nih.gov/35971803/
Dallari D, Stagni C, Rani N, Sabbioni G, Pelotti P, Torricelli P, Tschon M, Giavaresi G. Ultrasound-Guided Injection of Platelet-Rich Plasma and Hyaluronic Acid, Separately and in Combination, for Hip Osteoarthritis: A Randomized Controlled Study. Am J Sports Med. 2016 Mar;44(3):664-71. doi: 10.1177/0363546515620383. Epub 2016 Jan 21. PMID: 26797697.
https://pubmed.ncbi.nlm.nih.gov/26797697/
Gato-Calvo L, Magalhaes J, Ruiz-Romero C, Blanco FJ, Burguera EF. Platelet-rich plasma in osteoarthritis treatment: review of current evidence. Ther Adv Chronic Dis. 2019 Feb 19;10:2040622319825567. doi: 10.1177/2040622319825567. PMID: 30815245; PMCID: PMC6383098.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6383098/
Sánchez M, Guadilla J, Fiz N, Andia I. Ultrasound-guided platelet-rich plasma injections for the treatment of osteoarthritis of the hip. Rheumatology (Oxford). 2012 Jan;51(1):144-50. doi: 10.1093/rheumatology/ker303. Epub 2011 Nov 10. PMID: 22075062.
https://pubmed.ncbi.nlm.nih.gov/22075062/
ACHILLES:
Huang D, Vithran DTA, Gong HL, Zeng M, Tang ZW, Rao ZZ, Wen J, Xiao S. Effectiveness of platelet-rich plasma in the treatment of Achilles tendon disease. World J Orthop. 2023 Jun 18;14(6):485-501. doi: 10.5312/wjo.v14.i6.485. PMID: 37377997; PMCID: PMC10292057.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10292057/
Stanco D, Vigano’ M, Croiset SJ, De Girolamo L. Applications and limits of platelet-rich plasma in sports related injuries. J Biol Regul Homeost Agents. 2012 Apr-Jun;26(2 Suppl 1):53S-61S. PMID: 23648199.
https://pubmed.ncbi.nlm.nih.gov/23648199/
CARPAL TUNNEL:
Wu YT, Ho TY, Chou YC, Ke MJ, Li TY, Huang GS, Chen LC. Six-month efficacy of platelet-rich plasma for carpal tunnel syndrome: A prospective randomized, single-blind controlled trial. Sci Rep. 2017 Dec;7(1):94. doi: 10.1038/s41598-017-00224-6. Epub 2017 Mar 7. PMID: 28273894; PMCID: PMC5427966.
https://pubmed.ncbi.nlm.nih.gov/28273894/
Senna MK, Shaat RM, Ali AAA. Platelet-rich plasma in treatment of patients with idiopathic carpal tunnel syndrome. Clin Rheumatol. 2019 Dec;38(12):3643-3654. doi: 10.1007/s10067-019-04719-7. Epub 2019 Aug 16. PMID: 31420812.
https://pubmed.ncbi.nlm.nih.gov/31420812/
Malahias MA, Nikolaou VS, Johnson EO, Kaseta MK, Kazas ST, Babis GC. Platelet-rich plasma ultrasound-guided injection in the treatment of carpal tunnel syndrome: A placebo-controlled clinical study. J Tissue Eng Regen Med. 2018 Mar;12(3):e1480-e1488. doi: 10.1002/term.2566. Epub 2017 Dec 17. PMID: 28873284.
https://pubmed.ncbi.nlm.nih.gov/28873284/
ANKLE:
Wang C, Fan H, Li Y, Yun Z, Zhang Z, Zhu Q. Effectiveness of platelet-rich plasma injections for the treatment of acute Achilles tendon rupture: A systematic review and meta-analysis. Medicine (Baltimore). 2021 Oct 15;100(41):e27526. doi: 10.1097/MD.0000000000027526. PMID: 34731144; PMCID: PMC8519239.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8519239/
ELBOW:
Dejnek M, Moreira H, Płaczkowska S, Barg E, Reichert P, Królikowska A. Effectiveness of Lateral Elbow Tendinopathy Treatment Depends on the Content of Biologically Active Compounds in Autologous Platelet-Rich Plasma. J Clin Med. 2022 Jun 27;11(13):3687. doi: 10.3390/jcm11133687. PMID: 35806972; PMCID: PMC9267331.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9267331/
Watts AC, Morgan BW, Birch A, Nuttall D, Trail IA. Comparing leukocyte-rich platelet-rich plasma injection with surgical intervention for the management of refractory tennis elbow. A prospective randomised trial. Shoulder Elbow. 2020 Feb;12(1):46-53. doi: 10.1177/1758573218809467. Epub 2018 Nov 12. PMID: 32010233; PMCID: PMC6974885.
https://pubmed.ncbi.nlm.nih.gov/32010233/
Niemiec P, Szyluk K, Jarosz A, Iwanicki T, Balcerzyk A. Effectiveness of Platelet-Rich Plasma for Lateral Epicondylitis: A Systematic Review and Meta-analysis Based on Achievement of Minimal Clinically Important Difference. Orthop J Sports Med. 2022 Apr 8;10(4):23259671221086920. doi: 10.1177/23259671221086920. PMID: 35425843; PMCID: PMC9003647.
https://pubmed.ncbi.nlm.nih.gov/35425843/
Gupta PK, Acharya A, Khanna V, Roy S, Khillan K, Sambandam SN. PRP versus steroids in a deadlock for efficacy: long-term stability versus short-term intensity-results from a randomised trial. Musculoskelet Surg. 2020 Dec;104(3):285-294. doi: 10.1007/s12306-019-00619-w. Epub 2019 Aug 26. PMID: 31448392.
https://pubmed.ncbi.nlm.nih.gov/31448392/
POSTOPERATIVE:
Dinaki K, Grigoriadis N, Vizirianakis IS, Constantinidis J, Triaridis S, Karkos P. The impact of submucosal PRP injection on wound healing after endoscopic sinus surgery: a randomized clinical trial. Eur Arch Otorhinolaryngol. 2024 Jul;281(7):3587-3599. doi: 10.1007/s00405-024-08483-6. Epub 2024 Feb 9. PMID: 38334783; PMCID: PMC11211195.
https://pubmed.ncbi.nlm.nih.gov/38334783/
GENERAL:
Sundman EA, Cole BJ, Karas V, Della Valle C, Tetreault MW, Mohammed HO, Fortier LA. The anti-inflammatory and matrix restorative mechanisms of platelet-rich plasma in osteoarthritis. Am J Sports Med. 2014 Jan;42(1):35-41. doi: 10.1177/0363546513507766. Epub 2013 Nov 5. PMID: 24192391.
https://pubmed.ncbi.nlm.nih.gov/24192391/
Stanco D, Vigano’ M, Croiset SJ, De Girolamo L. Applications and limits of platelet-rich plasma in sports related injuries. J Biol Regul Homeost Agents. 2012 Apr-Jun;26(2 Suppl 1):53S-61S. PMID: 23648199.
https://pubmed.ncbi.nlm.nih.gov/23648199/
MULTIPLE INJECTIONS:
Yurtbay A, Say F, Çinka H, Ersoy A. Multiple platelet-rich plasma injections are superior to single PRP injections or saline in osteoarthritis of the knee: the 2-year results of a randomized, double-blind, placebo-controlled clinical trial. Arch Orthop Trauma Surg. 2022 Oct;142(10):2755-2768. doi: 10.1007/s00402-021-04230-2. Epub 2021 Oct 27. PMID: 34705072.
https://pubmed.ncbi.nlm.nih.gov/34705072/
Parmanantham M, Seenappa H, Das S, Shanthappa AH. Comparison of Functional Outcome of Single Versus Multiple Intra-articular Platelet-Rich Plasma Injection for Early Osteoarthritis Knee. Cureus. 2023 May 3;15(5):e38513. doi: 10.7759/cureus.38513. PMID: 37273322; PMCID: PMC10238762.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10238762/
McLarnon M, Heron N. Intra-articular platelet-rich plasma injections versus intra-articular corticosteroid injections for symptomatic management of knee osteoarthritis: systematic review and meta-analysis. BMC Musculoskelet Disord. 2021 Jun 16;22(1):550. doi: 10.1186/s12891-021-04308-3. PMID: 34134679; PMCID: PMC8208610.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8208610/
Barman A, Mishra A, Maiti R, Sahoo J, Thakur KB, Sasidharan SK. Can platelet-rich plasma injections provide better pain relief and functional outcomes in persons with common shoulder diseases: a meta-analysis of randomized controlled trials. Clin Shoulder Elb. 2022 Mar;25(1):73-89. doi: 10.5397/cise.2021.00353. Epub 2021 Nov 19. PMID: 34823313; PMCID: PMC8907495.